Most likely yes — if your printer supports direct thermal 4″ × 6″ labels. These “Zebra compatible” labels are sold specifically to work with Zebra desktop models (and many other direct-thermal brands like Rollo, Datamax, Sato, etc.), but not every single thermal machine (some die-cut or Dymo machines differ). If your printer is a Zebra desktop direct-thermal model, they’ll usually work fine — check your printer’s manual for “direct thermal” and 4″ label support.

Expect the common label standard of 4.00″ × 6.00″ (101.6 × 152.4 mm). Many sellers list the imperial size (4×6″), which converts to 101.6 × 152.4 mm — if you specifically need an exact 100 × 150 mm sheet, double-check the seller’s spec sheet before buying. Small metric rounding differences are common and usually fine for standard label sensors.

Use them in direct-thermal printers only. Direct-thermal labels have a heat-sensitive face that darkens with the printer head—they don’t require ribbon. Thermal-transfer printers need ribbon and transfer-compatible label stock; using the wrong stock will either not print correctly or damage parts. If your Zebra is a direct-thermal model (not thermal-transfer), these are the right choice.

They use a permanent acrylic adhesive that sticks well to corrugated boxes, most plastics and standard shipping surfaces — but not all extremes. Permanent adhesives are great for normal shipping/warehouse use and low temperatures, but they can fail on very oily, textured, or dirty surfaces. For long-term outdoor exposure or greasy environments, consider a specialist synthetic label or testing a sample first.

Direct-thermal labels are designed for short-to-medium-term use (shipping and indoor storage); they can fade with prolonged heat, sunlight, or abrasion. For indoor shipping and tracking in normal conditions, they’re fine; for long archival life or outdoor exposure, a thermal-transfer label or synthetic material is a better pick. Store unused labels in a cool, dark place to maximise shelf life.

Load the pack the way your printer expects (roll or fan-fold), set the printer to 4×6″ label size and the label type to “direct thermal”, and use the correct DPI (usually 203 or 300 DPI depending on the printer). Also check label orientation (black mark vs gap/perforation) and use the printer’s “calibrate media” function before a big print run. If labels are fan-folded, make sure the stack feeds smoothly; if on rolls, check the core ID and path. These simple checks cut misfeeds and smudging.